PDK1/PDHK1 Rabbit pAb, Unconjugated

Artikelnummer: ABB-A0834
Artikelname: PDK1/PDHK1 Rabbit pAb, Unconjugated
Artikelnummer: ABB-A0834
Hersteller Artikelnummer: A0834
Alternativnummer: ABB-A0834-100UL,ABB-A0834-20UL,ABB-A0834-500UL,ABB-A0834-1000UL
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, IF, WB
Spezies Reaktivität: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Konjugation: Unconjugated
Alternative Synonym: PDK1, PDK1/PDHK1
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.
Klonalität: Polyclonal
Molekulargewicht: 49kDa
NCBI: 5163
UniProt: Q15118
Reinheit: Affinity purification
Sequenz: STAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA
Target-Kategorie: PDK1
Antibody Type: Primary Antibody
Application Verdünnung: WB,1:500 - 1:1000|IF/ICC,1:50 - 1:200|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Cancer,Signal Transduction,PI3K-Akt Signaling Pathway,Endocrine Metabolism,Carbohydrate metabolism,Warburg Effect,Immunology Inflammation,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway