Mouse ALPL Protein, His Tag (active enzyme, MALS verified), Unconjugated, Human
Artikelnummer:
ABS-ALL-M52H3-100UG
Hersteller Artikelnummer:
ALL-M52H3-100ug
Alternativnummer:
ABS-ALL-M52H3-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Mouse
Konjugation:
Unconjugated
This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placentallike, and liver/bone/kidney (tissue nonspecific). The first three are located together on chromosome 2, while the tissue nonspecific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissuenonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. - Proteine/Peptide
