Rat ASGR1 / ASGPR1 Protein, Fc Tag, Unconjugated, Human
Artikelnummer:
ABS-AS1-R5253-100UG
Hersteller Artikelnummer:
AS1-R5253-100ug
Alternativnummer:
ABS-AS1-R5253-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Rat
Konjugation:
Unconjugated
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or Nacetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liverspecific drug delivery. The asialoglycoprotein receptor is a heterooligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] - Proteine/Peptide