OCT2 Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: OCT2 Antibody, Rabbit, Polyclonal
• Artikelnummer: ABT-AP52001
• Hersteller Artikelnummer: AP52001
• Alternativnummer: ABT-AP52001-100UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Alternative Synonym: Solute carrier family 22 member 2, Organic cation transporter 2, hOCT2, SLC22A2, OCT2

Produktbeschreibung

Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity.

Produkteigenschaften

• Klonalität: Polyclonal
• NCBI: 6582
• UniProt: O15244