IkappaB-alpha (Phospho-Tyr305) Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: IkappaB-alpha (Phospho-Tyr305) Antibody, Rabbit, Polyclonal
• Artikelnummer: ABT-AP52429
• Hersteller Artikelnummer: AP52429
• Alternativnummer: ABT-AP52429-100UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Alternative Synonym: NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Major histocompatibility complex enhancer-binding protein MAD3, NFKBIA, IKBA, MAD3, NFKBI

Produktbeschreibung

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Produkteigenschaften

• Klonalität: Polyclonal
• NCBI: 4792
• UniProt: P25963