PKM2 Antibody, Mouse, Monoclonal

Produktübersicht

• Artikelname: PKM2 Antibody, Mouse, Monoclonal
• Artikelnummer: ABT-AP52752
• Hersteller Artikelnummer: AP52752
• Alternativnummer: ABT-AP52752-100UL
• Hersteller: Abcepta
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Alternative Synonym: CTHBP ,Cytosolic thyroid hormone binding protein ,Cytosolic thyroid hormone-binding protein ,KPYM_HUMAN ,MGC3932 ,OIP 3 ,OIP-3 ,OIP3 ,OPA interacting protein 3 ,Opa-interacting protein 3 ,p58 ,PK muscle type ,PK, muscle type ,PK2 ,PK3 ,PKM ,PKM2 ,pykm ,Pyruvate kinase 2/3 ,Pyruvate kinase 3 ,Pyruvate kinase isozymes M1/M2 ,Pyruvate kinase muscle ,Pyruvate kinase muscle isozyme ,pyruvate kinase PKM ,Pyruvate kinase, muscle 2 ,TCB ,THBP1 ,Thyroid hormone binding protein 1 ,Thyroid hormone binding protein cytosolic ,Thyroid hormone-binding protein 1 ,Tumor M2 PK ,Tumor M2-PK .

Produktbeschreibung

Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.

Produkteigenschaften

• Klonalität: Monoclonal
• NCBI: 5315
• UniProt: P14618