CREB-1 (phospho Ser129) rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: CREB-1 (phospho Ser129) rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES4796
• Hersteller Artikelnummer: ES4796
• Alternativnummer: EBT-ES4796-50, EBT-ES4796-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human CREB around the phosphorylation site of Ser129. AA range:96-145
• Alternative Synonym: CREB1, Cyclic AMP-responsive element-binding protein 1, CREB-1, cAMP-responsive element-binding protein 1

Produktbeschreibung

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• NCBI: 1385
• UniProt: P16220

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Bilder

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using CREB (Phospho-Ser129) Antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using CREB (Phospho-Ser129) Antibody. The picture on the right is blocked with the phospho peptide.