NecroIr1

Produktübersicht

• Artikelname: NecroIr1
• Artikelnummer: MCE-HY-148365
• Hersteller Artikelnummer: HY-148365
• Alternativnummer: MCE-HY-148365-10MMX1ML,MCE-HY-148365-5MG,MCE-HY-148365-25MG,MCE-HY-148365-10MG,MCE-HY-148365-50MG,MCE-HY-148365-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

NecroIr1 is an iridium(III) complex, serves as necroptosis inducers in Cisplatin (HY-17394)-resistant lung cancer cells (A549R). NecroIr1 selectively accumulates in mitochondria, leading to oxidative stress and loss of mitochondrial membrane potential (MMP). NecroIr1 activates receptor-interacting serine-threonine kinase 3 (RIPK3) and Mixed Lineage Kinase (MLKL), and regulates CDK4 expression[1].

Produkteigenschaften

• Molekulargewicht: 823.36
• Reinheit: 98.02
• Formel: C40H29ClIrN5O
• Target-Kategorie: CDK,Mixed Lineage Kinase,RIP kinase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound