Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels[1][2].
Molekulargewicht:
266.25
Reinheit:
99.10
CAS Nummer:
[209799-67-7]
Formel:
C11H14N4O4
Target-Kategorie:
Apoptosis,Nucleoside Antimetabolite/Analog
Anwendungsbeschreibung:
Reference compound
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