Axl-IN-18, CAS [[3040329-68-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: Axl-IN-18, CAS [[3040329-68-5]] Preis auf Anfrage
• Artikelnummer: MCE-HY-162103
• Hersteller Artikelnummer: HY-162103
• Alternativnummer: MCE-HY-162103-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Axl-IN-18 (compound 25c) is a potent and selective type II AXL inhibitor. Axl-IN-18 shows excellent AXL inhibitory activity (IC50=1.1 nM) and 343-fold selectivity over the highly homologous kinase MET in biochemical assays (IC50=377 nM). Axl-IN-18 significantly inhibits AXL-driven cell proliferation, dose-dependently suppresses 4T1 cell migration and invasion, and induces apoptosis. Axl-IN-18 shows noticeable antitumor efficacy in a BaF3/TEL-AXL xenograft model[1].

Produkteigenschaften

• Molekulargewicht: 563.58
• CAS Nummer: [3040329-68-5]
• Formel: C32H26FN5O4
• Target-Kategorie: Apoptosis,TAM Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound