IL-4R alpha/CD124 Protein, Rat (HEK293, His)

Produktübersicht

• Artikelname: IL-4R alpha/CD124 Protein, Rat (HEK293, His)
• Artikelnummer: MCE-HY-P73217
• Hersteller Artikelnummer: HY-P73217
• Alternativnummer: MCE-HY-P73217-50UG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: IL-4R alpha/CD124 Protein, Rat (HEK293, His),Rat,HEK293

Produktbeschreibung

IL-4R alpha is a subunit alpha shared by IL-4 and IL-13 receptors, found in leukocytes originally. IL-4R alpha couples to the JAK1/2/3-STAT6 pathway and involves in promoting Th2 differentiation[1]. IL-4R alpha/CD124, Rat consists of 801 amino acids (M1-S801), exerts IL-4 binding function and results the phosphorylation of C-terminal tyrosine residues. IL-4R alpha/CD124, Rat has an immunoreceptor tyrosine inhibitor motif (ITIM) (698-703 a.a), which can bind to the SH2 domain of some phosphatases by phosphorylating ITIM. IL-4R alpha/CD124, Rat has a soluble form (1-229 a.a) and a transmembrane domain (233-256 a.a). The soluble IL-4R (sIL4R) inhibits IL4-induced spleen cell proliferation. IL-4R alpha/CD124 Protein, Rat is produced in HEK293 cells, including a Fibronectin typr III domain (125-223 a.a) and a C-Terminal His-tag.

Produkteigenschaften

• Molekulargewicht: Approximately 25.3 kDa
• Reinheit: 95
• Formel: 25084(Gene_ID)Q63257-1 (I26-R232)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins