Recombinant RET Proto-oncogene (Medullary Thyroid Carcinoma Marker) Antibody, IgG1, Clone: [r3F8], Mouse, Monoclonal

Artikelnummer: NBT-5979-MSM19-P0
Artikelname: Recombinant RET Proto-oncogene (Medullary Thyroid Carcinoma Marker) Antibody, IgG1, Clone: [r3F8], Mouse, Monoclonal
Artikelnummer: NBT-5979-MSM19-P0
Hersteller Artikelnummer: 5979-MSM19-P0
Alternativnummer: NBT-5979-MSM19-P0-20
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Human
Immunogen: Prokaryotic recombinant fusion protein corresponding to the extreme C-terminal cytoplasmic region of the human ret oncoprotein
Alternative Synonym: Cadherin family member 12 (CDHF12), Cadherin related family member 16 (CDHR16), ELKS, HSCR1, Hydroxyaryl protein kinase, MEN2A, MEN2B, MTC1, Multiple endocrine neoplasia and medullary thyroid carcinoma 1, Oncogene RET, Proto-oncogene c-Ret, Proto-oncogene tyrosine-protein kinase receptor ret, PTC, RET, RET ELE1, RET51, RET9
The ret-proto-oncogene encodes a cell surface glycoprotein belonging to the tyrosine-kinase receptor family. Three main splice variants have been identified. Immunoreactivity of the ret-proto-oncogene in normal tissue has been found in Schwann cells, sympathetic ganglion, adrenal medulla, astrocytes and cortical neurons.
Klonalität: Monoclonal
Klon-Bezeichnung: [r3F8]
Molekulargewicht: 150kDa (precursor), 170kDa (Mature)
Isotyp: IgG1
NCBI: 5979
UniProt: P07949
Formulierung: 200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified RET Proto-oncogene Recombinant Mouse Monoclonal Antibody (r3F8). Confirmation of Purity and Integrity of Antibody.
Western Blot Analysis of Human Brain tissue lysate using RET Oncogene Mouse Monoclonal Antibody (3F8). [Soluble RET Kinase Fragment]
Formalin-fixed, paraffin-embedded human colon carcinoma stained with RET Proto-oncogene Recombinant Mouse Monoclonal Antibody (r3F8). Inset: PBS instead of primary antibody, secondary only negative control.