Recombinant Major Vault Protein (MVP) Antibody, IgG1, Clone: [r1032], Mouse, Monoclonal
Artikelnummer:
NBT-9961-MSM4-P1
Hersteller Artikelnummer:
9961-MSM4-P1
Alternativnummer:
NBT-9961-MSM4-P1-100
Hersteller:
NeoBiotechnologies
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC, WB
Spezies Reaktivität:
Human
Immunogen:
Proteins precipitated from human breast cancer MCF-7 cells
Alternative Synonym:
Lung resistance-related protein (LRP), Major Vault Protein, MVP, VAULT1
Recognizes a protein of 104kDa-110kDa, characterized as major vault protein (MVP). Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Western Blot Analysis of Human Lung, Human Spleen tissue, Human Stomach and A549 lysates using Major Vault Protein Recombinant Rabbit Monoclonal Antibody (r1032).
SDS-PAGE Analysis of Purified MVP Recombinant Mouse Monoclonal Antibody (r1032). Confirmation of Purity and Integrity of Antibody.
Western blot analysis of U-87, A549 & SK-BR3 cell lysate using MVP Recombinant Mouse Monoclonal Antibody (r1032).
Formalin-fixed, paraffin-embedded human prostate stained with MVP Recombinant Mouse Monoclonal Antibody (r1032).
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
