A recombinant partial protein sequence (within amino acids 600-781) from the human protein was used as the immunogen for the Catenin Beta antibody.
Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. In normal tissues, beta-catenin is localized to the membrane of epithelial cells, consistent with its role in the cell adhesion complex.
