BCL6 Antibody / B-Cell Lymphoma 6 Protein, Clone: [PCRP-BCL6-1B1], Mouse, Monoclonal

Produktübersicht

• Artikelname: BCL6 Antibody / B-Cell Lymphoma 6 Protein, Clone: [PCRP-BCL6-1B1], Mouse, Monoclonal
• Artikelnummer: NSJ-V5021-100UG
• Hersteller Artikelnummer: V5021-100UG
• Alternativnummer: NSJ-V5021-100UG
• Hersteller: NSJ Bioreagents
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: FACS
• Spezies Reaktivität: Human
• Immunogen: A recombinant partial protein sequence (within amino acids 528-601) from the human protein was used as the immunogen for the BCL6 antibody.

Produktbeschreibung

Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL).The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( L&H ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [PCRP-BCL6-1B1]
• UniProt: P41182
• Reinheit: Protein A/G affinity
• Formulierung: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: Flow cytometry: 1-2ug/million cells
• Anwendungsbeschreibung: Optimal dilution of the BCL6 antibody should be determined by the researcher.