Entacapone sodium salt, CAS [[1047659-02-8]]

Artikelnummer: TGM-T11207
Artikelname: Entacapone sodium salt, CAS [[1047659-02-8]]
Artikelnummer: TGM-T11207
Hersteller Artikelnummer: T11207
Alternativnummer: TGM-T11207-25MG, TGM-T11207-50MG, TGM-T11207-100MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Entacapone sodium salt inhibits catechol-O-methyltransferase(COMT) with similar IC50 in different tissues including live, duodenum, kidney and lung, but entacapone is more active than tolcapone in those tissues. Entacapone (< 100 µM) is a potent inhibitor of alpha-syn and beta-amyloid (Abeta) oligomerization and fibrillogenesis, and also protects against extracellular toxicity induced by the aggregation of both proteins in PC12 cells.Entacapone sodium salt is a specific, potent, peripherally acting catechol-O-methyltransferase (COMT) inhibitor with IC50 of 151 nM for PD treatment.
Molekulargewicht: 328.28
CAS Nummer: [1047659-02-8]
Formel: C14H15N3NaO5
Target-Kategorie: Others|||Transferase
T11207