FMF-04-159-2 is a potent covalent cell cycle protein-dependent kinase 14 (CDK14) inhibitor with IC50 of 39.6 nM for CDK14 and 256 nM for CDK2.FMF-04-159-2 is able to reduce alpha-synuclein (alpha-Syn ) aggregation in neurons and plays a role in Parkinsons disease models, and also inhibits triple-negative breast cancer (TNBC) progression and metastasis by attenuating Wnt/beta-catenin signaling.
Molekulargewicht:
683.01
Reinheit:
96.57%
CAS Nummer:
[2364489-81-4]
Formel:
C28H30Cl3N7O5S
Target-Kategorie:
Others|||Wnt/beta-catenin|||CDK
T11309
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten