MCP2 (Macrophage/Monocyte Chemotactic Protein 2, Monocyte Chemotactic Protein 2, MCP-2, C-C Motif Chemokine 8, Chemokine (C-C Motif) Ligand 8, CCL8, HC14, Monocyte Chemoattractant Protein 2, Small Inducible Cytokine A8, SCYA8, SCY
Artikelnummer:
USB-M2750-08A-BIOTIN
Hersteller Artikelnummer:
M2750-08A-Biotin
Alternativnummer:
USB-M2750-08A-BIOTIN-100
Hersteller:
US Biological
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ELISA, WB
Immunogen:
Recombinant protein corresponding to human MCP-2, expressed in E. coli.
MCP-2 acts as a chemoattractant for monocytes, lymphocytes, eosinophils and basophils, due to its ability to bind to the common MCP receptor, chemokine (C-C motif) receptor 2 (CCR2), and also CCR1 and CCR3. Proteolytic cleavage of MCP-2 into the NH2-terminally truncated form, MCP-2 (6-76), results in the loss of chemotactic activity, forming a functional C-C chemokine inhibitor, which may be important during inflammatory responses. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
