UCS Diagnostic Srl has developed CytoMatrix at the Bio-Medico Campus of the University of Rome: A synthetic matrix that morphologically preserves biological material (cells, tumor biopsies) from fine needle aspirates (FNA) in their three-dimensional structure. This results in enormous benefits for routine diagnostics and offers new options for research.
CytoMatrix (Art. Nr. CM140) is a porous support for trapping minimal amounts of cells , e.g. the material from a needle aspiration, and preserves structure (by formalin fixation and paraffin embedding), thus generating optimal conditions for various routine diagnostic tests: Hematoxylin-Eosin (H&E), Immunohistochemistry (IHC), Molecular Pathology (FISH).
CytoMatrix can easily allow the phenotypic characterization of small amounts of cancer cells and allows to faithfully preserve the features of the original tumour. This makes it an essential and in some cases indispensable and irreplaceable tool for a complete and accurate diagnosis.
Brushini S et al. CytoMatrix for a reliable and simple characterization of lung cancer stem cells from malignant pleural effusions. J Cell Physiol. 235(3): 1877–1887 (2020) / doi: 10.1002/jcp.29121
|Dog: B Cell Lymphoma, CD20||Thyroid: ADENOMA||Ovarian Ca ascites (EGFR E746-A750 del.)||Breast needle aspiration EE||FNA Thyroid Perls Stain (40X)|
|Pulmonary needle aspiration ADC||Pleural effusion||Gastric GIST Antrum DOG1 (100X)||Pleural effusion from breast cancer||Urovysion on Urine|
|Cranial theca bone detail||Bone marrow aspirate: CD138, (plasma cells) 20X||ck7 in ascites of ovarian k||Lung ADK, PD-L1 (40X)||Pulmonary needle aspiration ADC|
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