DHRS2 Antibody, Rabbit, Polyclonal

Catalog Number: ABT-AP51756
Article Name: DHRS2 Antibody, Rabbit, Polyclonal
Biozol Catalog Number: ABT-AP51756
Supplier Catalog Number: AP51756
Alternative Catalog Number: ABT-AP51756-100UL
Manufacturer: Abcepta
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human, Mouse, Rat
Alternative Names: Dehydrogenase/reductase SDR family member 2, mitochondrial, 111-, Dicarbonyl reductase HEP27, Protein D, DHRS2
Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2- propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.
Clonality: Polyclonal
NCBI: 10202
UniProt: Q13268