PIK3R6 Antibody, Rabbit, Polyclonal

Catalog Number: ABT-AP51817
Article Name: PIK3R6 Antibody, Rabbit, Polyclonal
Biozol Catalog Number: ABT-AP51817
Supplier Catalog Number: AP51817
Alternative Catalog Number: ABT-AP51817-100UL
Manufacturer: Abcepta
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human, Mouse, Rat
Alternative Names: Phosphoinositide 3-kinase regulatory subunit 6, Phosphoinositide 3-kinase gamma adapter protein of 87 kDa, p84 PI3K adapter protein, p84 PIKAP, p87 PI3K adapter protein, p87PIKAP, PIK3R6, C17orf38
Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis, signaling seems to involve RRAS.
Clonality: Polyclonal
NCBI: 146850
UniProt: Q5UE93