Kv7.1 Antibody, Rabbit, Polyclonal

Catalog Number: ABT-AP51822
Article Name: Kv7.1 Antibody, Rabbit, Polyclonal
Biozol Catalog Number: ABT-AP51822
Supplier Catalog Number: AP51822
Alternative Catalog Number: ABT-AP51822-100UL
Manufacturer: Abcepta
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human, Mouse, Rat
Alternative Names: Potassium voltage-gated channel subfamily KQT member 1, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1, KQT-like 1, Voltage-gated potassium channel subunit Kv71, KCNQ1, KCNA8, KCNA9, KVLQT1
Probably important in cardiac repolarization. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current. Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors. May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea.
Clonality: Polyclonal
NCBI: 3784
UniProt: P51787