RIN1 Antibody, Rabbit, Polyclonal

Catalog Number: ABT-AP51833
Article Name: RIN1 Antibody, Rabbit, Polyclonal
Biozol Catalog Number: ABT-AP51833
Supplier Catalog Number: AP51833
Alternative Catalog Number: ABT-AP51833-100UL
Manufacturer: Abcepta
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human, Mouse, Rat
Alternative Names: Ras and Rab interactor 1, Ras inhibitor JC99, Ras interaction/interference protein 1, RIN1
Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
Clonality: Polyclonal
NCBI: 9610
UniProt: Q13671