MAGEA6 Antibody, Rabbit, Polyclonal

Catalog Number: ABT-AP51889
Article Name: MAGEA6 Antibody, Rabbit, Polyclonal
Biozol Catalog Number: ABT-AP51889
Supplier Catalog Number: AP51889
Alternative Catalog Number: ABT-AP51889-100UL
Manufacturer: Abcepta
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human, Mouse, Rat
Alternative Names: Melanoma-associated antigen 6, Cancer/testis antigen 16, CT16, MAGE-6 antigen, MAGE3B antigen, MAGEA6, MAGE6
Proposed to enhance ubiquitin ligase activity of RING- type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.
Clonality: Polyclonal
NCBI: 4105
UniProt: P43360