NOX4 Antibody, Rabbit, Polyclonal

Product Overview

• Article Name: NOX4 Antibody, Rabbit, Polyclonal
• Biozol Catalog Number: ABT-AP52013
• Supplier Catalog Number: AP52013
• Alternative Catalog Number: ABT-AP52013-100UL
• Manufacturer: Abcepta
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human, Mouse, Rat
• Alternative Names: NADPH oxidase 4, 163-, Kidney oxidase-1, KOX-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase, NOX4, RENOX

Product Description

Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 4 displays an increased activity. Isoform 5 and isoform 6 display reduced activity.

Product Properties

• Clonality: Polyclonal
• NCBI: 50507
• UniProt: Q9NPH5