IkappaB-alpha (Phospho-Tyr305) Antibody, Rabbit, Polyclonal

Product Overview

• Article Name: IkappaB-alpha (Phospho-Tyr305) Antibody, Rabbit, Polyclonal
• Biozol Catalog Number: ABT-AP52429
• Supplier Catalog Number: AP52429
• Alternative Catalog Number: ABT-AP52429-100UL
• Manufacturer: Abcepta
• Host: Rabbit
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Alternative Names: NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Major histocompatibility complex enhancer-binding protein MAD3, NFKBIA, IKBA, MAD3, NFKBI

Product Description

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Product Properties

• Clonality: Polyclonal
• NCBI: 4792
• UniProt: P25963