JNJ-38158471(KDR) is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with IC50=40nM. It also inhibits closely related tyrosine kinases, Ret (180nM) and Kit (500nM). It has no significant activity (>1 microM) against VEGFR-1 and VEG
Molecular Weight:
364.8
CAS Number:
[951151-97-6]
Formula:
C15H17ClN6O3
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