Recombinant Human APN Protein (C-6His)

Catalog Number: EBT-EPT136
Article Name: Recombinant Human APN Protein (C-6His)
Biozol Catalog Number: EBT-EPT136
Supplier Catalog Number: EPT136
Alternative Catalog Number: EBT-EPT136-10
Manufacturer: ELK Biotechnology
Category: Proteine/Peptide
Alternative Names: Aminopeptidase N, ANPEP, AP-M, APN, AP-N, CD13 antigen, CD13, CD13APN, PEPN, PEPNhAPN
Recombinant Human Aminopeptidase N is produced by our Mammalian expression system and the target gene encoding Lys69Lys967 is expressed with a 6His tag at the C-terminus.
Molecular Weight: Molecular weight: 103.5 KDa. Apparent molecular weight: 110-130 KDa, reducing conditions
UniProt: P15144
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Application Notes: Background: ANPEP gene encodes aminopeptidase N (APN) also known as microsomal aminopeptiase, alanyl aminopeptidase, aminopeptidase M, CD13, or membrane protein p161, is a member of the peptidase M1 family. Widely expressed in many cells, tissues and species, APN cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. Probably plays a role in regulating growth and differentiation of early B-lineage cells. It also may play a role in the catabolic pathway of the renin-angiotensin system. It degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure