CQ-16 is an orally active small molecule drug conjugate (SMDC) targeting prostate-specific membrane antigen (PSMA). CQ-16 exhibits highly selective antiproliferative activity between PSMA-positive and PSMA-negative prostate cells. In addition, CQ-16 also has PARP inhibitory activity (IC50=1 nM). (Pink: PSMA Ligand (HY-139840), Black: Linker (HY-W037980), Blue: PARP Inhibitor (HY-10162))[1]
Molecular Weight:
850.85
CAS Number:
[3024354-59-1]
Formula:
C40H47FN8O12
Target:
PARP,PSMA
Application Notes:
Reference compound
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