Mavatrep (JNJ-39439335) is an orally active, selective and potent TRPV1 antagonist with high affinity for hTRPV1 channels (Ki=6.5 nM). Mavatrep antagonizes capsaicin-induced Ca2+ influx with an IC50 value of 4.6 nM. Mavatrep can be used in some studies of neuropathic pain[1].
Molecular Weight:
422.44
Purity:
99.67
CAS Number:
[956274-94-5]
Formula:
C25H21F3N2O
Target:
TRP Channel
Application Notes:
Reference compound
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