ARS-853 is a cell-active, selective, covalent KRAS G12C inhibitor with an IC50 of 2.5 µM. ARS-853 inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation[1][2].
Molecular Weight:
432.94
Purity:
98.39
CAS Number:
[1629268-00-3]
Formula:
C22H29ClN4O3
Target:
Apoptosis,Ras
Application Notes:
Reference compound
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