LJI308, CAS [[1627709-94-7]]

Product Overview

• Article Name: LJI308, CAS [[1627709-94-7]]
• Biozol Catalog Number: MCE-HY-19713
• Supplier Catalog Number: HY-19713
• Alternative Catalog Number: MCE-HY-19713-10MG,MCE-HY-19713-10MMX1ML,MCE-HY-19713-5MG,MCE-HY-19713-25MG,MCE-HY-19713-100MG,MCE-HY-19713-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

LJI308 is a potent pan-ribosomal S6 kinase (RSK) inhibitor, with IC50s of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. LJI308 inhibits the phosphorylation of RSK (T359/S363) and YB-1 (S102) after irradiation, treatment with EGF, and in cells expressing a KRAS mutation[1][2].

Product Properties

• Molecular Weight: 368.38
• Purity: 99.07
• CAS Number: [1627709-94-7]
• Formula: C21H18F2N2O2
• Target: Ribosomal S6 Kinase (RSK),YB-1

Application Notes

• Application Notes: Reference compound