IL-10 Protein, a key immune regulator, mitigates inflammation by binding to its receptor (IL10RA/IL10RB), activating JAK1 and STAT2, leading to STAT3-mediated anti-inflammatory gene expression. IL-10 targets APCs, reducing pro-inflammatory cytokines and hindering antigen presentation. It controls macrophage inflammation through metabolic reprogramming. Existing as a homodimer, IL-10 interacts with IL10RA/IL10RB. IL-10 Protein, Feline is the recombinant IL-10 protein, expressed by E. coli , with tag free.
Molecular Weight:
Approximately 19 kDa, based on SDS-PAGE under reducing conditions.
Purity:
98.00
Formula:
493683(Gene_ID)P55029 (S19-I178)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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