IL-12 beta Protein, also known as natural killer cell stimulatory factor 2, is a common subunit (p40) of IL-12 and IL-23. IL-12 is a inflammatory factor expressed by activated macrophages, and involves in Th1-type immune response against cancer[1]. IL-12 beta Protein located outside the cell membrane, involves in singalling mediated by Jak-STAT[3]. IL-12 beta Protein consists of 335 amino acids (M1-S335) with a fibronectin type-III domain (233-324 a.a). IL-12 beta Protein, Mouse (M1-S335) is produced in HEK293 cells with a C-Terminal hFc-tag.
Molecular Weight:
Approximately 83 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formula:
16160(Gene_ID)P43432 (M23-S335)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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