IL-18 protein is a pro-inflammatory cytokine that plays an important role in epithelial barrier repair and immune response regulation by polarizing T helper 1 (Th1) cells and natural killer (NK) cells. After binding to IL18R1 and IL18RAP receptors, IL-18 forms a signaling ternary complex, activates NF-kappa-B, and induces inflammatory mediators. IL-18 Protein, Mouse (solution) is the recombinant mouse-derived IL-18 protein, expressed by E. coli , with tag free.
Molecular Weight:
Approximately 19 kDa, based on SDS-PAGE under reducing conditions.
Purity:
98.00
Formula:
16173(Gene_ID)P70380 (N36-S192)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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