IL-18 protein is a pro-inflammatory cytokine that is critically involved in epithelial barrier repair and regulates immune responses, especially Th1 cell and NK cell immune responses. IL-18 binds to IL18R1 and IL18RAP receptors to form a signaling ternary complex, activate NF-kappa-B, and induce inflammatory mediators. IL-18 Protein, Rhesus Macaque (His) is the recombinant Rhesus Macaque-derived IL-18 protein, expressed by E. coli , with N-6*His, labeled tag.
Molecular Weight:
Approximately 24.39 kDa, based on SDS-PAGE under reducing conditions.
