IL-23R Protein, critical in immune response, forms the interleukin-23 receptor by associating with IL12RB1. Binding to IL23, it activates T-cells, NK cells, and potentially macrophage/myeloid cells through Jak-Stat signaling. Associated with autoimmune diseases and tumorigenesis, IL-23R, in the presence of IL12RB1, forms a heterodimeric IL-23 receptor, interacting with JAK2 and activating STAT3. IL-23R Protein, Human (HEK293, Fc) is the recombinant human-derived IL-23R protein, expressed by HEK293 , with C-hFc labeled tag.
Molecular Weight:
Approximately 90-110 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Purity:
96.60
Formula:
149233(Gene_ID)AAM44229.1 (G24-D353)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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