Thianthrene is a potent and orally active inhibitor of Leishmania donovani pteridine reductase 1 (PTR1). Thianthrene is a sulfur-containing tricyclic molecule distributed widely within the macro-structure of hydrocarbon fossil fuels. Thianthrene inhibits the intracellular amastigotes of Leishmania donovani (IC50 = 23 µM). Thianthrene has a moderate anthelmintic activity. Thianthrene appears to inhibit RNA function and subsequent protein production. Thianthrene can stimulate liver regeneration in vivo[1][2].
Molecular Weight:
216.33
Purity:
99.99
CAS Number:
[92-85-3]
Formula:
C12H8S2
Target:
Biochemical Assay Reagents,Parasite
Application Notes:
MCE Product type: Reference compound
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