Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammation. Elubrixin is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.
Molecular Weight:
463.31
Purity:
98.65%
CAS Number:
[688763-64-6]
Formula:
C17H17Cl2FN4O4S
Target:
Interleukin|||CXCR|||IL Receptor
T11179
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