iLite IL-2*

Produktübersicht

• Artikelname: iLite IL-2*
• Artikelnummer: EUD-BM4002
• Hersteller Artikelnummer: BM4002
• Alternativnummer: EUD-BM4002
• Hersteller: Svar Life Science
• Kategorie: Zellen/Zellkultur

Zusatzinformationen

The iLite® IL-2 assay enables sensitive quantification of IL-2 activity or inhibition. Ideal for immunotherapy development and functional assessment of IL-2-targeting biologics.

• High sensitivity and large dynamic range
• "Assay-ready" format for rapid and convenient use
• Reproducible and biologically relevant results
• Reduced assay variability and higher reproducibility compared to cells in culture
• Normalization of cell counts and serum matrix effects using a second reporter gene

 

Product Overview

iLite® IL-2 Assay Ready Cells is a genetically engineered reporter gene cell line optimized to respond to IL-2 with proportional expression of Firefly Luciferase. These cells allow for the testing of specific IL-2 activity and screening for unwanted inhibitory activity of IL-2.

iLite IL-2 assay ready cells are avian DT-40 cells (ATCC# CRL-2111) which have been genetically engineered and optimized to be responsive to IL-2, resulting in a proportional expression of Firefly Luciferase.

Normalization of cell counts, and serum matrix effects is obtained by a second reporter gene, a Renilla Luciferase reporter gene construct, under control of a constitutive promotor.

The ATCC® CRL-2111 cell line is used under a license from ATCC®

 

What's in the box?

>250 µL of Assay Ready Cells suspended in cryoprotective medium. 

 

Specifications

• Product code: BM4002
• Assay target: IL-2
• Size: 1 vial corresponding to one 96 well plate
• Technology: Cell-based reporter gene assay
• Detection system: Luminescence
• Regulatory status: Research Use Only

 

Produkteigenschaften

• Formulierung: Assay Ready Cells

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