iLite IL-23*

Produktübersicht

• Artikelname: iLite IL-23*
• Artikelnummer: EUD-BM4023
• Hersteller Artikelnummer: BM4023
• Alternativnummer: EUD-BM4023
• Hersteller: Svar Life Science
• Kategorie: Zellen/Zellkultur

Zusatzinformationen

This iLite® IL-23 assay enables precise measurement of IL-23-induced signaling in a cell-based context. Ideal for characterizing inhibitors and monitoring potency in autoimmune drug development.

• High sensitivity and large dynamic range
• "Assay-ready" format for rapid and convenient use
• Reproducible and biologically relevant results
• Reduced assay variability and higher reproducibility compared to cells in culture
• Normalization of cell counts and serum matrix effects using a second reporter gene

 

Product Overview

iLite® IL-23 Assay Ready Cells are a highly specific genetically engineered reporter gene cell line based on avian DT-40 cells (ATCC#CRL2111). They are optimized to respond to IL-23 with specific, proportional expression of Firefly Luciferase without cross-reactivity to IL-12.

Lite® IL-23 Assay Ready Cells can be used as both a sensitive and specific assay for the quantification of the potency of anti-IL-23 or anti-p40 drugs. Because the cells respond specifically to IL-23, they can be used as an assay for the development of specific p19 inhibitors.

Normalization of cell counts and serum matrix effects is obtained by a second reporter gene, a Renilla Luciferase reporter gene construct, under control of a constitutive promotor.

The ATCC® CRL-2111 cell line is used under a license from ATCC®

 

What's in the box?

>250 µl of Assay Ready Cells suspended in cryoprotective medium.

 

Specifications

• Product code: BM4023
• Assay target: IL-23
• Size: 1 vial corresponding to one 96 well plate
• Technology: Cell-based reporter gene assay
• Detection system: Luminescence
• Regulatory status: Research Use Only

 

Produkteigenschaften

• Formulierung: Assay Ready Cells

Bilder

IL-23