ILite TNF-alpha Xcel*
- Bilder (1)
| Artikelname: | ILite TNF-alpha Xcel* |
| Artikelnummer: | EUD-BM4044 |
| Hersteller Artikelnummer: | BM4044 |
| Alternativnummer: | EUD-BM4044 |
| Hersteller: | Svar Life Science |
| Kategorie: | Zellen/Zellkultur |
Pre-qualified and assay-ready, iLite® TNF-α Xcel Cells provide rapid and sensitive detection of TNF-α activity – streamlining workflows for potency testing and neutralization assays.
Product OverviewiLite® TNF-alpha Xcel Assay Ready Cells provide a means of directly quantifying both the potency and neutralizing antibody response to TNF-alpha antagonists of diverse structure in the same assay, making it an outstanding tool for biosimilar development. The assay is a simple and easy test format which detects anti-TNF alpha activity and, indirectly, the presence of anti-drug antibodies. Measuring the functional activity of TNF-alpha, the assay can be used for both potency and immunogenicity assessments of TNF-alpha inhibitors in the same assay and the iLite TNF-alpha Xcel Assay Ready Cells also provide a means of directly comparing a biosimilar and innovator product in the same assay. iLite® TNF-alpha Xcel Assay Ready Cellsare engineered cells for use in a normalized reporter gene bioassay for screening of anti-TNF alpha activity in samples, resulting in a proportional expression of Firefly Luciferase. Binding of TNF-alpha to its receptor results in activation of the NFkB regulated Firefly luciferase reporter gene construct. iLite® TNF-alpha Xcel Assay Ready Cells also contain the Renilla Luciferase reporter gene, under the control of a constitutive promoter.
What's in the box?>250 µL of iLite® Assay Ready Cells suspended in cryoprotective medium.
Specifications
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TNF-alpha |
