iLite IL-6*

Produktübersicht

• Artikelname: iLite IL-6*
• Artikelnummer: EUD-BM4061
• Hersteller Artikelnummer: BM4061
• Alternativnummer: EUD-BM4061
• Hersteller: Svar Life Science
• Kategorie: Zellen/Zellkultur

Zusatzinformationen

This reporter gene assay delivers reproducible, cell-based detection of IL-6 bioactivity — supporting the characterization of inflammatory response modulators and anti-IL-6 therapeutics.

• High sensitivity and large dynamic range
• "Assay-ready" format for rapid and convenient use
• Reproducible and biologically relevant results
• Reduced assay variability and higher reproducibility compared to cells in culture
• Normalization of cell counts and serum matrix effects using a second reporter gene

 

Product Overview

iLite® IL-6 Assay Ready Cells is a genetically engineered reporter gene cell line, based on the human embryonic kidney cell line, HEK293, and genetically engineered and optimized to be responsive to human IL-6. The cells' response to IL-6 results in a proportional expression of Firefly Luciferase.

These cells allow for the testing of specific IL-6 activity and screening for unwanted inhibitory activity of IL-6. The activity of IL-6 and its agonist and antagonist can be assayed in a functional and biologically relevant format.

Normalization of cell counts, and serum matrix effects is obtained by a second reporter gene, a Renilla Luciferase reporter gene construct, under the control of a constitutive promotor.

 

What's in the box?

>250 µL of Assay Ready Cells suspended in cryoprotective medium.
 

 

Specifications

• Product code: BM4061
• Assay target: IL-6
• Size: 1 vial corresponding to one 96 well plate
• Technology: Cell-based reporter gene assay
• Detection system: Luminescence
• Regulatory status: Research Use Only

 

Produkteigenschaften

• Formulierung: Assay Ready Cells

Bilder

IL-6