Artikelnummer: BOT-BNC041479-100

CD3e (T-Cell Marker) (PC3/188A), CF405S conjugate, 0.1mg/mL, IgG1, Clone: [PC3/188A], Mouse, Monoclonal

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The immunogen for this Mab is derived from the cytoplasmic domain of CD3 epsilon chain. CD3 consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

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Artikelname:	CD3e (T-Cell Marker) (PC3/188A), CF405S conjugate, 0.1mg/mL, IgG1, Clone: [PC3/188A], Mouse, Monoclonal
Artikelnummer:	BOT-BNC041479-100
Hersteller-Artikelnummer:	BNC041479-100
Alternativnummer:	BOT-BNC041479-100-100UL
Hersteller:	Biotium
Wirt:	Mouse
Kategorie:	Antikörper
Anwendung:	IHC, WB
Spezies-Reaktivität:	Human
Immunogen:	Synthetic peptide corresponding to amino acids 156-168 (ERPPPVPNPDYEP) of the cytoplasmic domain of human CD3e
Konjugation:	CF405S
Alternative Namen:	CD 3E\|CD3 epsilon\|CD3 TCR complex\|CD3E\|CD3e antigen epsilon polypeptide (TiT3 complex)\|T cell antigen receptor complex epsilon subunit of T3\|T-cell surface antigen T3/Leu-4 epsilon chain\|T-cell surface glycoprotein CD3 epsilon chain\|T3E\|TCRE\|TiT3 complex

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