Artikelnummer: BOT-BNC400056-500

CD74(LN-2), CF640R conjugate, 0.1mg/mL, Clone: [LN-2], Mouse, Monoclonal

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This antibody recognizes a protein of ~35 kDa, identified as CD74 (Workshop IV). CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

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Artikelname:	CD74(LN-2), CF640R conjugate, 0.1mg/mL, Clone: [LN-2], Mouse, Monoclonal
Artikelnummer:	BOT-BNC400056-500
Hersteller-Artikelnummer:	BNC400056-500
Alternativnummer:	BOT-BNC400056-500-500UL
Hersteller:	Biotium
Wirt:	Mouse
Kategorie:	Antikörper
Anwendung:	FC, IF, IHC
Spezies-Reaktivität:	Human, Mouse, Primate
Immunogen:	SU-DHL-4 lymphoma cells
Konjugation:	CF640R
Alternative Namen:	CLIP, DHLAG, Gamma chain of class II antigens, HLA class II histocompatibility antigen gamma chain, HLA-DR antigens-associated invariant chain, HLADR-gamma (HLADG), Ia antigen-associated invariant chain, la-gamma, Major histocompatibility complex class II invariant chain, MHC HLA-DR gamma chain

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