Artikelnummer: BOT-BNC941342-100

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1342), CF594 conjugate, 0.1mg/mL, Clone: [CFTR/1342], Mouse, Monoclonal

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This antibody recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3,5-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

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Artikelname:	CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1342), CF594 conjugate, 0.1mg/mL, Clone: [CFTR/1342], Mouse, Monoclonal
Artikelnummer:	BOT-BNC941342-100
Hersteller-Artikelnummer:	BNC941342-100
Alternativnummer:	BOT-BNC941342-100-100UL
Hersteller:	Biotium
Wirt:	Mouse
Kategorie:	Antikörper
Anwendung:	IHC
Spezies-Reaktivität:	Human, Mouse
Immunogen:	Recombinant human full-length CFTR
Konjugation:	CF594
Alternative Namen:	ABC35, ATP Binding Cassette Superfamily C Member 7 (ABCC7), cAMP-dependent chloride channel, CFTR, CFTR/MRP, Channel conductance-controlling ATPase, Cystic Fibrosis Transmembrane Conductance Regulator, MRP7, TNR CFTR

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