Produktbeschreibung
The YTS 191 monoclonal antibody reacts with mouse CD4. The CD4 antigen is a 55 kDa type I cell-surface membrane glycoprotein belonging to the immunoglobulin superfamily. CD4 acts as a co-receptor which in cooperation with the T cell receptor (TCR) interacts with class II MHC molecules displayed by antigen presenting cells (APC). CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally. The YTS 191 antibody has been shown to compete with clones GK1.5 and YTS 177 for CD4 binding.
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