Artikelnummer: BXC-BE0289

InVivoMAb anti-mouse TIM-1 (CD365), Clone: [3B3], Rat, Monoclonal

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Produktbeschreibung

The 3B3 monoclonal antibody reacts with mouse T cell immunoglobulin and mucin domain 1 (TIM-1) also known as CD365. TIM-1 is a type I cell-surface glycoprotein and member of the Ig superfamily. TIM-1 is preferentially expressed on TH2 cells and has been identified as a stimulatory molecule for T cell activation. The TIM gene family, plays critical roles in regulating the immune response to viral infection. TIM-1 is also involved in allergic responses, asthma, and transplant tolerance. The 3B3 antibody is an agonistic antibody and has been shown to activate TIM-1 in vivo and in vitro resulting in the hyperproliferation of T cells and induction of proinflammatory cytokine production.

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Artikelname:	InVivoMAb anti-mouse TIM-1 (CD365), Clone: [3B3], Rat, Monoclonal
Artikelnummer:	BXC-BE0289
Hersteller-Artikelnummer:	BE0289
Alternativnummer:	BXC-BE0289-1MG,BXC-BE0289-5MG,BXC-BE0289-25MG,BXC-BE0289-50MG,BXC-BE0289-100MG
Hersteller:	Bio X Cell
Wirt:	Rat
Kategorie:	Antikörper
Spezies-Reaktivität:	Mouse
Immunogen:	Mouse TIM-1 (signal and IgV domains)/mouse IgG2a Fc fusion protein

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