Artikelnummer: BXC-BE0296-INDUSTRIAL

InVivoMAb anti-mouse 4-1BB (CD137), Clone: [17B5], Golden Hamster, Monoclonal

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Produktbeschreibung

The 17B5 monoclonal antibody reacts with mouse 4-1BB, a TNF receptor superfamily member also known as CD137. 4-1BB is a 39 kDa transmembrane protein expressed by T lymphocytes, NK cells, dendritic cells, granulocytes, and mast cells. Upon binding its ligand 4-1BBL, 4-1BB provides costimulatory signals to both CD4 and CD8 T cells through the activation of NF-kappaB, c-Jun and p38 downstream pathways. The importance of the 4-1BB pathway has been underscored in several diseases, including cancer. The 17B5 antibody has been shown to block 4-1BB-mediated T cell proliferation in vitro.

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Verfügbarkeit3 Tage

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Artikelname:	InVivoMAb anti-mouse 4-1BB (CD137), Clone: [17B5], Golden Hamster, Monoclonal
Artikelnummer:	BXC-BE0296-INDUSTRIAL
Hersteller-Artikelnummer:	BE0296
Alternativnummer:	BXC-BE0296-1MG,BXC-BE0296-5MG,BXC-BE0296-25MG,BXC-BE0296-50MG,BXC-BE0296-100MG
Hersteller:	Bio X Cell
Wirt:	Golden Hamster
Kategorie:	Antikörper
Spezies-Reaktivität:	Mouse
Immunogen:	Not available or unknown

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