CAS Number: 108334-68-5 Molecular Weight: 1506.92 Salt Form: Acetate Purity: >96% Sequence (3-letter): Pro-Leu-Ala-Arg-Thr-Leu-Ser-Val-Ala-Gly-Leu-Pro-Gly-Lys-Lys-OH Sequence (1-letter): PLARTLSVAGLPGKK-OH Storage: -20 ?C or below Solubility: Soluble in water (1 mg/ml) Syntide 2 is a synthetic peptide recognized as a substrate by Ca?? calmodulin-dependent protein kinase II and Ca?? phospholipid-dependent protein kinase (PKC). The sequence is homologous to phosphorylation site 2 on glycogen synthase. Syntide 2 has been used as a probe to assay localization of CaMKII activity and to study the effects of point mutations on phosphorylation activity.
References
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Enslen, H. et al. (1994) ?Characterization of Ca2+/calmodulin-dependent protein kinase IV. Role in transcriptional regulation? J. Biol. Chem. 269: 15520-15527. 2. Yamazaki, T. et al. (1996) ?Endothelin-1 Is Involved in Mechanical Stress-induced Cardiomyocyte Hypertrophy? J. Biol. Chem. 271: 3221-3228.
